Psalm 94:19, "In the multitude of my thoughts within me, your comforts delight my soul," speaks to a common human experience: the battle we often face with overwhelming anxieties and worries. Let's break down the meaning:

"In the multitude of my thoughts within me..." This phrase describes a mind filled with a vast array of thoughts. It's not just a few stray ideas, but a "multitude" suggesting an overwhelming volume. This could represent anxieties, fears, doubts, uncertainties, worries about the future, or regrets about the past. The phrase "within me" emphasizes the internal, personal nature of these struggles. It's a private mental turmoil.

"...your comforts delight my soul." This is the contrast and the solution. Even amidst the chaotic storm of thoughts, the speaker finds solace and joy in God's "comforts." The word "comforts" refers to God's presence, promises, and provision. It's the reassurance that comes from knowing God is with them, caring for them, and offering hope. The word "delight" implies a deep, soul-satisfying joy and peace. It's not just a temporary relief, but a profound and lasting comfort that transforms the inner state. "Soul" suggests the innermost being, the very core of the person, is being comforted.

In essence, the verse means:

When I am overwhelmed with anxieties, worries, and a flood of unsettling thoughts, the comfort I find in God's presence and promises brings deep joy and peace to my soul.

Here's a deeper understanding:

Acknowledges the Reality of Mental Struggle: The verse doesn't deny the existence or intensity of negative thoughts. It acknowledges that everyone experiences internal mental struggles.
Highlights the Power of Faith: It shows the power of faith to provide solace and peace in the face of those struggles. God's comfort is not a denial of reality, but a source of strength and hope within it.
Emphasizes a Personal Relationship with God: The speaker isn't just relying on abstract concepts, but on a personal relationship with God. It's God's comforts, implying a direct interaction and experience of His presence.
Offers Hope: The verse provides a message of hope and reassurance. It suggests that even when our minds are filled with anxiety, we can find comfort and delight in God.

Practical Applications:

Turn to God in Times of Anxiety: When facing overwhelming thoughts, actively seek God's comfort through prayer, Scripture reading, worship, or connecting with a faith community.
Focus on God's Promises: Remind yourself of God's promises of love, provision, and protection. Dwell on His faithfulness in the past.
Practice Gratitude: Focusing on the blessings in your life can shift your perspective away from anxious thoughts and toward God's goodness.
Seek Support: Don't be afraid to reach out to trusted friends, family members, or a therapist for support and guidance. Remember that seeking help is a sign of strength, not weakness.

The verse is a powerful reminder that even in the midst of mental turmoil, we can find lasting peace and joy in God's comforting presence.